Album was composed by Stephen Trask and was released on December 14, 2010. Soundtrack consists of 22 tracks tracks with duration over about 45 minutes. Album was released by Universal Studios.
CD 1
| 1 | Greg's Theme (Main Titles)Stephen Trask | 02:43 |  |
| 2 | The Byrnes Family TreeStephen Trask | 01:54 | |
| 3 | I Am FlamencoStephen Trask | 01:49 | |
| 4 | Enema, MIG Fighter and Andi GarciaStephen Trask | 01:08 | |
| 5 | The GodfockerStephen Trask | 03:19 | |
| 6 | An Interesting CoupleStephen Trask | 01:32 | |
| 7 | Early Human School Industrial ReelStephen Trask | 01:13 | |
| 8 | Dump TruckStephen Trask | 01:06 | |
| 9 | Chicago Train ChaseStephen Trask | 01:58 | |
| 10 | Getting Off the Hamster WheelStephen Trask | 01:20 | |
| 11 | Sustengo With a Nasonex ChaserStephen Trask | 02:59 | |
| 12 | InterrogationStephen Trask | 01:40 | |
| 13 | One Pill Makes You...Stephen Trask | 02:20 | |
| 14 | StandoffStephen Trask | 02:09 | |
| 15 | Bernie Gets a SemiStephen Trask | 01:19 | |
| 16 | Focker Family MakeupStephen Trask | 01:24 | |
| 17 | Suite: Piece of Cake / Land Shark / Suck It! / Meow / SchtuppStephen Trask | 03:41 | |
| 18 | The GregfockerStephen Trask | 01:48 | |
| 19 | Oy Vey, Christmaka / Google YourselfStephen Trask | 01:49 | |
| 20 | Byrnes, Jack Byrnes RemixJoseph Bonn | 01:04 | |
| 21 | Greg's JamStephen Trask | 02:25 | |
| 22 | Greg's Jam Alt (Bonus Track)Stephen Trask | 02:20 | |
