Album was composed by Michael Kamen and was released on September 08, 2009. Soundtrack consists of 15 tracks tracks with duration over more than hour. Album was released by Buena Vista Pictures Distribution, Inc..
CD 1
| 1 | Cruella de VilDr. John | 04:08 |  |
| 2 | One Hundred and One Dalmatians (Main Titles) / Good Morning, Pongo / Walking the DogL.A. All Star Orchestra | 03:56 | |
| 3 | The House of de Vil (Cruella's Catwalk) / Love At First Sight / Roger Goes SwimmingL.A. All Star Orchestra | 06:56 | |
| 4 | Daisy, Daisy (Anita Goes Swimming)L.A. All Star Orchestra | 02:04 | |
| 5 | The Wedding (Cup of Marriage) / Horace and Jasper / SkinnerL.A. All Star Orchestra | 07:05 | |
| 6 | Going to Have a Puppy / I Adore PuppiesL.A. All Star Orchestra | 02:41 | |
| 7 | Birth (15 Puppies) / The HeistL.A. All Star Orchestra | 07:19 | |
| 8 | Kipper the Die Hard DogL.A. All Star Orchestra | 01:29 | |
| 9 | Woof On the RoofL.A. All Star Orchestra | 03:26 | |
| 10 | RescueL.A. All Star Orchestra | 02:09 | |
| 11 | Kipper Finds the PuppiesL.A. All Star Orchestra | 05:18 | |
| 12 | Pup, Pup, Pup, Pup, PuppiesL.A. All Star Orchestra | 04:17 | |
| 13 | Reunion In the BarnL.A. All Star Orchestra | 05:19 | |
| 14 | Puppies In the MistL.A. All Star Orchestra | 02:00 | |
| 15 | Home - One Big Happy FamilyL.A. All Star Orchestra | 03:44 | |
