Album was composed by and was released on May 18, 2018. Soundtrack consists of 21 tracks tracks with duration over . Album was released by Atlantic Records.
CD 1
| 1 | A Cautionary TaleBarrett Wilbert Weed & Grey Henson | | |
| 2 | It RoarsErika Henningsen & Original Broadway Cast of Mean Girls | | |
| 3 | Where Do You Belong?Grey Henson, Barrett Wilbert Weed, Erika Henningsen & Original Broadway Cast of Mean Girls | | |
| 4 | Meet the PlasticsGrey Henson, Barrett Wilbert Weed, Taylor Louderman, Ashley Park, Kate Rockwell & Erika Henningsen | | |
| 5 | Stupid With LoveErika Henningsen & Original Broadway Cast of Mean Girls | | |
| 6 | Apex PredatorBarrett Wilbert Weed & Erika Henningsen | | |
| 7 | What's Wrong With Me?Ashley Park | | |
| 8 | Stupid With Love (Reprise)Kyle Selig & Erika Henningsen | | |
| 9 | SexyKate Rockwell & Original Broadway Cast of Mean Girls | | |
| 10 | Someone Gets HurtTaylor Louderman, Kyle Selig & Original Broadway Cast of Mean Girls | | |
| 11 | Revenge PartyGrey Henson, Barrett Wilbert Weed, Erika Henningsen & Original Broadway Cast of Mean Girls | | |
| 12 | FearlessErika Henningsen, Ashley Park, Kate Rockwell & Original Broadway Cast of Mean Girls | | |
| 13 | StopGrey Henson, Kate Rockwell & Original Broadway Cast of Mean Girls | | |
| 14 | What's Wrong With Me? (Reprise)Kerry Butler & Ashley Park | | |
| 15 | Whose House Is This?Cheech Manohar, Erika Henningsen, Ashley Park, Kate Rockwell & Original Broadway Cast of Mean Girls | | |
| 16 | More Is BetterErika Henningsen & Kyle Selig | | |
| 17 | Someone Gets Hurt (Reprise)Barrett Wilbert Weed & Grey Henson | | |
| 18 | World BurnTaylor Louderman & Original Broadway Cast of Mean Girls | | |
| 19 | I'd Rather Be MeBarrett Wilbert Weed & Original Broadway Cast of Mean Girls | | |
| 20 | Do This ThingErika Henningsen, Kerry Butler, Cheech Manohar, Mathletes & Original Broadway Cast of Mean Girls | | |
| 21 | I See StarsErika Henningsen & Original Broadway Cast of Mean Girls | | |
