Album was composed by Alan Menken and was released on March 14, 2006. Soundtrack consists of 17 tracks tracks with duration over about 55 minutes. Album was released by Walt Disney Records.
CD 1
| 1 | Big DogAkon | 03:38 |  |
| 2 | Man's Best FriendCharlie B. | 03:06 | |
| 3 | Atomic DogGeorge S. Clinton | 04:43 | |
| 4 | Every Dog Has Its DayJaJa Biggs | 02:52 | |
| 5 | Somethin' About YouThe Doghouse Biscuit Band | 03:18 | |
| 6 | Woof! There It IsThe Shaggy Dog | 03:02 | |
| 7 | It's a DogKyle Massey | 02:40 | |
| 8 | Tibet (Score)Alan Menken | 02:31 | |
| 9 | First Signs (Score)Alan Menken | 02:58 | |
| 10 | Transformation (Score)Alan Menken | 04:02 | |
| 11 | Magic Lab (Score)Alan Menken | 02:17 | |
| 12 | Breaking Through (Score)Alan Menken | 02:47 | |
| 13 | Kozak Get's a Tail (Score)Alan Menken | 02:31 | |
| 14 | Meditation (Score)Alan Menken | 01:03 | |
| 15 | Escaping the Lab (Score)Alan Menken | 04:40 | |
| 16 | To the Rescue (Score)Alan Menken | 04:51 | |
| 17 | Family Time (Score)Alan Menken | 01:20 | |
